--- title: "QuickGO (EBI GO Annotation Browser)" task: "" lineage_type: import upstream_source: https://github.com/K-Dense-AI/scientific-agent-skills/blob/9c9bd2e9/skills/database-lookup/references/quickgo.md upstream_sha: 9c9bd2e9 imported_at: 2026-06-26 prompt_class: prompt upstream_changes: accepted author: upstream validated: false --- # QuickGO (EBI GO Annotation Browser) ## Base URL ``` https://www.ebi.ac.uk/QuickGO/services/ ``` ## Auth No auth required. ## Key Endpoints | Endpoint | Description | |----------|-------------| | `/ontology/go/terms/{goId}` | GO term details | | `/ontology/go/terms/{goId}/children` | Child terms | | `/ontology/go/terms/{goId}/ancestors` | Ancestor terms | | `/ontology/go/search?query={term}` | Search GO terms by keyword | | `/annotation/search` | Search annotations by gene/taxon/GO term | ## Annotation Search Parameters - `goId` — GO term (e.g. GO:0003723) - `taxonId` — NCBI taxonomy (e.g. 9606 for human) - `geneProductId` — UniProt accession - `evidence` — evidence code (e.g. ECO:0000269) - `aspect` — biological_process, molecular_function, cellular_component - `limit`, `page` — pagination ## Example Calls ``` # GO term details https://www.ebi.ac.uk/QuickGO/services/ontology/go/terms/GO:0003723 # Human annotations for RNA binding https://www.ebi.ac.uk/QuickGO/services/annotation/search?goId=GO:0003723&taxonId=9606&limit=10 # Search terms by keyword https://www.ebi.ac.uk/QuickGO/services/ontology/go/search?query=apoptosis&limit=5 ``` ## Response Format JSON. Annotations: paginated results with gene product, GO term, evidence, qualifier. ## Rate Limits EBI fair-use policy. Use download endpoint for large result sets.