drug-discovery-prompts/upstream/K-Dense-AI-scientific-agent-skills/skills/database-lookup/references/gwas-catalog.md

title, task, lineage_type, upstream_source, upstream_sha, imported_at, prompt_class, upstream_changes, author, validated

title	task	lineage_type	upstream_source	upstream_sha	imported_at	prompt_class	upstream_changes	author	validated
GWAS Catalog (EBI)		import	https://github.com/K-Dense-AI/scientific-agent-skills/blob/9c9bd2e9/skills/database-lookup/references/gwas-catalog.md	9c9bd2e9	2026-06-26	prompt	accepted	upstream	false

GWAS Catalog (EBI)

Base URL

https://www.ebi.ac.uk/gwas/rest/api

Auth

No API key required.

Note: Responses use HAL+JSON format with _links and _embedded keys.

Key Endpoints

Endpoint	Description
/studies/{accession}	Single study (e.g. GCST001633)
/studies/search/findByPubmedId?pubmedId={id}	Studies by PubMed ID
/singleNucleotidePolymorphisms/{rsId}	SNP details
/singleNucleotidePolymorphisms/{rsId}/associations	Associations for a SNP
/singleNucleotidePolymorphisms/search/findByRsId?rsId={rsId}	Search by rsID
/associations	List associations
/associations/{id}	Single association
/efoTraits	List EFO traits
/efoTraits/search/findByEfoTrait?trait={name}	Search traits

Pagination

?page=0&size=20 (zero-indexed, max ~500)

Example Calls

# Get a study
https://www.ebi.ac.uk/gwas/rest/api/studies/GCST001633

# Associations for a SNP
https://www.ebi.ac.uk/gwas/rest/api/singleNucleotidePolymorphisms/rs7329174/associations

# Search traits
https://www.ebi.ac.uk/gwas/rest/api/efoTraits/search/findByEfoTrait?trait=diabetes&page=0&size=5

Response Format

HAL+JSON. Results in _embedded.studies[] or _embedded.associations[]. Key fields: pvalue, riskFrequency, orPerCopyNum, betaNum.

Rate Limits

No published limit. Bulk data via FTP at ftp.ebi.ac.uk/pub/databases/gwas/